Antibiotics developer Cempra Pharmaceuticals is one of three healthcare companies expected to go public this week.
A total of eight initial public offerings are expected this week, according to Renaissance Capital, a Greenwich, Connecticut research firm specializing in initial public offerings. Besides Chapel Hill, North Carolina-based Cempra’s planned $86 million IPO, the other healthcare-related IPOs on Renaissance’s radar for this week are Greenway Medical Technologies and Merrimack Pharmaceuticals.
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Cempra’s two lead drug candidates are antibiotics that would address drug-resistant bacteria. Cempra is targeting an antibiotics market Datamonitor estimates was $19.6 billion in the United States, Japan and the five major European markets in 2009.
Proceeds from the Cempra IPO will finance late-stage clinical trials on two antibiotic candidates targeting drug-resistant bacteria. CEM-101, also called solithromycin, is ready to enter phase 3 clinical trials as a pneumonia treatment. The antibiotic treatment could also have applications in Legionnaires’ disease and sexually transmitted diseases such as syphilis. Cempra reported positive phase 2 clinical trial results for the antibiotic last September, just prior to the firm’s October IPO filing.
A second candidate called Taksta has finished phase 2 clinical trials and would be studied in phase 3 as a treatment for skin infections, including MRSA (Methicillin-resistant Staphylococcus aureus ). Cempra earlier this month updated its filings and set a price range of $11 to $13 per share for the IPO.
Cempra’s IPO is expected to be joined by two other healthcare-related public stock offerings. Georgia health IT firm Greenway Medical Technologies, which provides IT software for ambulatory healthcare providers, expects to raise up to $80 million by selling shares in the $11 to $13 per share range. Merrimack Pharmaceuticals, a Massachusetts firm that has technology to discover and develop novel cancer treatments, plans to raise $173 million by selling shares in the $8 to $10 range.