Roche
-
Roche to Pay $7.1B to Get Contender in Tight Inflammatory Bowel Disease Race
Roche’s Telavant acquisition comes as the Roivant Sciences subsidiary prepares its main asset for Phase 3 testing in ulcerative colitis. The antibody drug candidate blocks a novel target for inflammation and fibrosis that’s also the focus of clinical-stage programs of other big pharma companies.
-
Do you advise self-insured employers? You Can Help Us!
Take part in this survey and share some of the trends you are seeing among your clients across healthcare, including chronic conditions, behavioral health and navigation.
-
Roche Deal Aims to Get Molecular Glues to Stick to Elusive Cancer, Neuro Targets
Roche is paying $50 million up front to begin a drug R&D alliance with Monte Rosa Therapeutics, a biotech whose molecular glue technology could address targets previously deemed undruggable. It’s Roche’s second such deal in the past month.
-
Roche Expands Into RNAi Through Alnylam Alliance on Hypertension Drug
Alnylam pioneered RNA interference drugs for rare disease. The biotech aims to bring RNAI to prevalent disorders and its alliance with Roche on the drug zilebesiran for hypertension better positions the company to achieve this goal.
-
FDA Approves Roche Lymphoma Drug, Bringing Competition to New AbbVie Med
The FDA approved Roche’s Columvi as a third-line treatment for a type of blood cancer called diffuse large B-cell lymphoma. This new Roche drug will compete against Epkinly, AbbVie’s recently approved DLBCL drug.
-
Roche Forks Over $70M for Brain-Penetrating Cancer Drug Candidate
Roche is acquiring global rights to a Zion Pharma Limited drug candidate with potential applications treating breast cancer that has metastasized to the brain. The small molecule, currently in Phase 1 testing, is designed to penetrate the blood-brain barrier.
-
New FDA Nod for Roche Drug Moves It to the Front Line in Treating Blood Cancer
Roche’s Polivy is now approved as an earlier line of treatment for patients who have diffuse large B-cell lymphoma. Accelerated approval of the drug in 2019 had made the drug a third treatment option for patients with advanced cases of this type of blood cancer.
-
Roche Drug for Rare Blood Disorder Hits Phase 3 Goals; Regulatory Filings Are Next
AstraZeneca dominates the market for drugs that treat rare blood disorder paroxysmal nocturnal hemoglobinuria. Roche drug crovalimab met the two main goals of its pivotal test, and if approved, would offer a dosing edge compared to AstraZeneca’s two blockbuster PNH medicines.
-
Trayt Health Seeks to Increase Access to Diagnoses and Treatments
CEO Malekeh Amini explains how Trayt Health can bridge the gap for patients seeking neurological care.
-
Healthcare Hires of Note
Read about executive hires across healthcare and life sciences.
-
Roche Withdraws Immunotherapy in U.S. for Bladder Cancer After Failed Study
Tecentriq failed to beat chemotherapy in improving overall survival, the main goal of its confirmatory Phase 3 test in bladder cancer. The drug had been granted accelerated approval based on results from a single-arm Phase 2 clinical trial.
-
Roche shells out $250M to acquire Good Therapeutics and its preclinical oncology program
Roche announced it will acquire Good Therapeutics, a Seattle-based preclinical biotech, for $250 million. The deal makes Roche responsible for developing and commercializing Good’s lead program, which seeks to make oncology drugs that target PD-1 proteins more effective, such as Keytruda or Opdivo.
-
Roche pays $55M for late-stage drug for rare kidney disease with no approved treatment
An Ionis Pharmaceuticals drug has positive Phase 2 results in immunoglobulin A nephropathy, leading Roche to exercise its option to license the rights to the molecule. The pharmaceutical giant gets a contender in the chase to win the first regulatory approval of a therapy for this rare kidney disease.
-
Roche bispecific drug Lunsumio lands European nod in follicular lymphoma
Follicular lymphoma patients in Europe now have a new treatment option. The European Commission approved Roche drug Lunsumio, a bispecific antibody designed to go after two targets to treat advanced cases of this type of cancer.
-
Repare relinquishes cancer drug to Roche, gets $125M to finance growing pipeline
Roche’s deep oncology pipeline is adding a drug candidate from Repare Therapeutics that works by interfering with a DNA repair mechanism of cancer cells. Repare receives $125 million up front and it retains the right to share in the development and commercialization of the drug, camonsertib.