MedCity News

This Week In Epic News: FTC Probe, AI Agents & More

Ambros Therapeutics’ Path for Pain Drug Goes Through Reverse Merger With Werewolf

Along with Ambros Therapeutics’ merger with Werewolf Therapeutics, the combined company will raise $150 million in a private placement. Ambros is in Phase 3 testing with a drug developed for treating a type of pain that does not respond to currently available medicines, including opioids.

By Frank Vinluan

MedCity Influencers

The Pulse of Innovation: How 3D Models Can Prepare Surgeons for the Operating Room

Today, 3D modeling and printing technology can make a dramatic impact — even shortening some operations by 30-90 minutes. Looking ahead, that reduction will only grow as the technology is further integrated and becomes more advanced.

By Justin Ryan

MedCity Influencers

Wooden mannequin holding a US $100 dollar bill on a defocused stethoscope background.

Modernizing Payment Integrity in an Era of Systemic Fraud

Gaps in reimbursement oversight and recovery will only widen, unless plans modernize how they detect, investigate, and recoup improper payments.

By Christian Bass

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Payers

SCAN, Costco Launch Medicare Partnership

SCAN Health Plan and Costco are partnering to provide a suite of insurance products for seniors.

By Marissa Plescia

BioPharma, Pharma

Ultragenyx Gene Therapy Becomes First FDA-Approved Treatment for Ultra-Rare Disease

Ultragenyx Pharmaceutical’s Genglycos received accelerated FDA approval for glycogen storage disease type Ia, an inherited enzyme deficiency. It’s also the first approved gene therapy for Ultragenyx, which specializes in rare disease treatments.

By Frank Vinluan

Opinion

The Imperative of Distinguishing Medical-Grade Devices from Wellness Tech

Why the flood of consumer wellness devices demands clear boundaries between lifestyle improvement and clinical diagnostics

By Dave Albert

MedCity Influencers

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AI in Pharmacovigilance: Why Governance Will Define Success

As adoption accelerates, organizations must ensure that the use of AI strengthens and not weakens accountability and patient safety.

By Anuradha (Annie) Prabhakar

Devices & Diagnostics, Health Tech

Happy Health Snags $75M to Support Home-Based Care

Happy Health's $75 million round was from ARCH Venture Partners and OpenLoop.

By Marissa Plescia

Where Will AI Deployment Benefit Payers the Most?

We are taking a look at how health insurers are using AI, defining success, and managing cybersecurity risks. Give us your opinions by completing our brief, anonymous survey.

By MedCity News

BioPharma, Pharma

Merck, Moderna Personalized mRNA Cancer Therapy Achieves a First for Melanoma

Merck and Moderna said intismeran autogene, an mRNA cancer vaccine that prompts an immune response to proteins expressed by a patient’s tumors, met the main goal of a pivotal test in melanoma. It’s the most advanced trial in a 50/50 partnership evaluating the personalized cancer treatment in a wide range of tumor types.

By Frank Vinluan

Opinion

Why Bone Health Is Preventive Healthcare’s Next Big Category

The next healthcare revolution isn't about treating osteoporosis, it's about preserving mobility and healthspan.

By Laura Yecies

Consumer / Employer

Included Health Taps Carrum Health for Value-Based Specialty Care

Included Health is partnering with Carrum Health to provide high-quality specialty care while reducing costs for employers.

By Marissa Plescia

BioPharma, Pharma

Amylyx Plans FDA Filing After GLP-1 Drug Hits Trial Goals in Rare Metabolic Condition

Amylyx Pharmaceuticals’ avexitide led to statistically significant and clinically meaningful reductions in hypoglycemic events in patients with post-bariatric hypoglycemia (PBH). This peptide drug, a GLP-1 antagonist, was acquired from Eiger BioPharmaceuticals in 2024.

By Frank Vinluan

MedCity Influencers

Rural US Healthcare Has A Cybersecurity Problem — CMS Funding Can Help Fix the Part No One Sees

Rural hospitals need trained people, tested backups, downtime procedures, clinical continuity planning, and staff who know what to do when an alert fires. A framework won’t substitute for that work, but it helps organize it and makes progress measurable.

By Bimal Sheth

Payers

KFF: Insurers Denied 12%-18% of Prior Authorization Requests in 2025

KFF found that insurers denied 12%-18% of standard prior authorization requests in 2025, with significant variation among insurers and gaps in transparency.

By Marissa Plescia

BioPharma, Pharma

Slate Medicines’ Merger and $245M Private Placement Fuel Mission in Migraine

Migraine drugs developer Slate Medicines is going public in a reverse merger with Fulcrum Therapeutics. The biotech’s lead antibody drug blocks two novel migraine targets, offering the potential for better efficacy compared to other next-generation migraine drugs in R&D.

By Frank Vinluan

Events, Devices & Diagnostics

The Rise of Consumer Diagnostics and Emerging Trends

Consumer diagnostics will be one of several discussions at the INVEST Digital Health conference focused on power shifting to the consumer in healthcare. The conference is scheduled for October 29 in Dallas at Pegasus Park, in partnership with Health Wildcatters.

By Stephanie Baum

MedCity Influencers

Artificial Intelligence hologram robot and futuristic UI panel.

Healthcare Is Deploying AI Tools — It’s Not Ready for AI Colleagues

Most healthcare organizations are experimenting with AI. Few are preparing to manage AI agents as participants in everyday healthcare workflows.

By Sagnik Bhattacharya