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FDA greenlights trial of BCG vaccine for Type 1 diabetes, Shire aiming for Actelion? (Morning Read)

The five year study of 150 people will be led by Massachusetts General clinician Denise Faustman

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Massachusetts General Hospital Immunobiology Laboratory Director Denise Faustman will head up a five-year Phase 2 clinical trial to evaluate whether a tuberculosis vaccine could be used to treat adults 18-60 with Type 1 diabetes. The study, which the FDA greenlighted, was announced at the American Diabetes Scientific Sessions over the weekend.

“We have learned a lot since the early studies in mice — not just about how BCG works but also about its potential therapeutic benefits, similar to what are being seen in trials against other autoimmune diseases,” said Faustman. “We are so grateful to all of the donors, large and small, who have made this trial possible — especially the Iacocca Foundation, which has believed in us and has been a supporter since our early days. Our goal is to complete enrollment and also to raise the remaining funds needed for the trial by the end of this year.”

Shire is interested in acquiring Actelion for $18.3 billion (£12 billion), according to a report in The Sunday Times.

LIFE SCIENCES

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TECH

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POLITICS

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ALITTLE EXTRA

A new website wants to keep track of failed startups called Autopsy.io. It includes the company’s concept, reason for failure, blog entries with “the full story” behind the company’s decline and the twitter handle of the founder. So far, no sign that healthcare startups were included, but it’s only a matter of time.

Photo: Flickr user Matt Cam Easarat