Heart-valve replacement procedures are complicated for many reasons. Having a foreign material in the body presents challenges like increased inflammation and potential revision surgery, which is not only challenging physically for a patient, it’s also costly.
For that reason, Zurich, Switzerland-based Xeltis has developed its Endogenous Tissue Restoration (ETR) technology, which uses bioabsorable polymers that encourages the body’s natural healing process and eventually gets resorbed into the tissue.
The company has successfully completed its second feasibility trial and is currently aiming for CE mark approval for a pulmonary valve in 2018.
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The technology was created by professor Jean-Marie Lehn, whose Nobel Prize–winning research on supramolecular chemistry led to its development. The bioabsorable cardiovascular patch essentially works as valves, vessels and tissue until the body has produced enough tissue to take over naturally.
In the company’s most recent study, the bioabsorable patch was implanted in children born with only a single functioning heart ventricle. The company reported, according to Plastics Today, that there were no complications or functional impairments after the operations.
“The technology we are developing is not a one-product technology—it’s a platform technology that can be applied to a multitude of cardio-vascular treatments,” Xeltis CEO Laurent Grandidier stated.
Private equity company LSP out of Amsterdam co-led a €27 million Series B fund in 2014, which was one of the largest investments to date by the European healthcare investor.
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Photo: Screenshot via Xeltis.com
