Breakthroughs in physics have reshaped everything from communications to consumer electronics. Yet these methods remain rare in medical practice, where healthcare costs continue to climb, and development cycles can last decades. This mismatch became apparent in my own medical journey long ago when timely imaging revealed a brain tumor. That single procedure saved my life. The device that scanned my head, however, has not grown more affordable or significantly smaller since then.
Some researchers are using familiar physics at safe levels to selectively affect cancer cells, pathogens and even specific neurons. They have shown it is possible to match frequencies to unhealthy cells and damage them without harming surrounding tissue. This approach has been known in scientific circles for years. The question is why it remains unavailable to most patients who could benefit.
Part of the issue lies in the complexity and expense of traditional research and development. Some pathways to regulatory approval cost hundreds of millions of dollars and span more than a decade. These long timelines discourage broad collaboration. Investigators tend to focus on a narrow condition and then try to recover their enormous costs by charging high prices per patient. That creates an unfortunate cycle. Treatments may work in small trials but never make it to everyday clinics because few people or institutions can afford them.
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We have seen open frameworks in software and hardware accelerate improvements and cut down on duplication of effort. Shared platforms are familiar to engineers, designers and even smartphone users. Yet, we rarely see that same collaborative mindset in healthcare. Safety data remain locked in individual labs. Teams often rebuild early-stage prototypes rather than building on validated ones. The procedures used to validate the technology on humans (IRBs) are sequestered and confidential, preventing the creation of unified datasets. There is a logical way to change this. Groups could share findings on safety and performance and experimental processes to co-develop devices that work in multiple conditions. Each new trial would add to a collective pool of knowledge instead of repeating the same basic steps. All of this can generate revenues and profits for those who adapt. That strengthens regulatory evaluations and lowers development costs as well.
Stroke care is one area where faster progress could save lives. With earlier imaging or ultrasound-based treatment, more patients might receive timely life-saving procedures. Mental health, especially treatment-resistant depression, might also benefit from precisely targeted effects on overactive neurons. For cancer, resonance-based approaches that do not require chemicals or radiation might complement or ideally replace existing therapies. All these possibilities hinge on clearing away the structural barriers that keep scientific advances out of the clinic.
Sharing data across institutions is not just an efficiency measure. It speeds up discovery and opens space for multiple collaborators to refine applications for different ailments. It also encourages global input. Technology can scale when scientists, clinicians and engineers join forces rather than operate in isolation. This addresses both a technical and a human challenge. There are limitations to what a single group can accomplish when they must handle everything from hardware development to trial design to regulatory outreach. Pooling resources and expertise shorten time-to-approval and reduces overhead.
The decades to come may feature more diseases that do not respond well to conventional treatments. The scientific community has tools that can intervene in new ways, but the gap between lab data and clinical access remains too wide. Cooperation through open platforms, robust testing and shared safety data can lower that barrier. With each success, a broader spectrum of diagnoses can be tackled.
Healthcare has strong players. Hospitals, device makers and government agencies all serve essential functions. Yet without a more open model, we will continue to halt promising approaches in their earliest phases. There is a clear benefit to applying modern physics and consumer manufacturing methods to medical challenges. If we harness the ideas that already drove down costs in computing, we stand a better chance of helping millions of people in need of timely care for stroke, cancer, mental health disorders and more.
We are living in a moment when many realize that collaboration yields better, faster and more affordable advances. Open source also enables the potential for bigger profits and revenue. What’s in reach: a small amount of money paid for treatments across millions of people, rather than business as usual: expensive lifesaving treatments only for the few who can afford them. Can you imagine life if we kept smartphones only for the very rich? When laboratories, clinicians and regulators share data, reduce repetitive steps and refine technologies for broader use, it becomes far easier to translate new science into effective therapies more broadly. That is worth prioritizing. Our best hope for better outcomes is to apply what we already know about the success of open development in technology and practical physics to the greatest health needs of our time.
Photo: eichinger julien, Getty Images
Mary Lou Jepsen, PhD is the Founder, CEO, and Chairman of Openwater.health, a company that develops medical technology integrating semiconductor physics, light, and sound to diagnose and treat diseases at the cellular level. Openwater aims to make hospital-grade medical care accessible worldwide. The company's platform combines infrared imaging, ultrasound, and electromagnetic fields. Openwater collaborates with leading institutions to validate its technology and drive healthcare innovation. Using open-source principles and consumer electronics manufacturing, Openwater seeks to reduce medical device development time and costs. Jepsen has been named to Time Magazine's 100 Most Influential People and CNN's Top 10 Thinkers. A former executive at Facebook, Oculus, Google and Intel, Jepsen founded four hardware companies including One Laptop per Child (OLPC). Jepsen is a former MIT Professor with 250 published or issued patents.
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