Lilli Health, a digital health company, launched a new app last week to help people manage polycystic ovary syndrome (PCOS), a hormonal imbalance that creates irregular menstrual cycles.
Houston-based Lilli Health is focused on treating PCOS with a “low insulin lifestyle.” About 95% of women with PCOS have elevated insulin levels, which disrupt hormone balance by prompting the ovaries to produce more androgens, such as testosterone, according to the company. This causes many of the main symptoms of PCOS, including irregular periods, acne, unwanted hair growth, weight gain and ovulation challenges. The Lilli Health platform offers at-home insulin testing kits, educational materials and personalized lab interpretation.
With the newly launched Lilli App, consumers get access to meal plans and recipes that are meant to support a low-insulin lifestyle. They also gain access to a symptom-tracking tool, menstrual cycle insights and educational resources on how to lower insulin levels. In addition, users can upload lab results from their provider or use the company’s metabolic testing kits.
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The app is important because “it marks a real shift in how we approach PCOS — not just managing symptoms like irregular periods, acne, or weight gain, but actually targeting the underlying metabolic dysfunction driving those symptoms. Lilli gives women access to real data, real tools, and a clear path forward, something the current healthcare system rarely provides,” said Dr. Ali Chappell, founder of Lilli Health, in an email.
Full access to the app costs consumers $14.99 a month. The company primarily sells to consumers, though it’s exploring partnerships with employers and fertility benefit platforms.
It’s estimated that 6-13% of reproductive-aged women battle PCOS, and about 70% of affected women are undiagnosed, according to the World Health Organization. It is also the leading cause of infertility.
Chappell created Lilli Health due to her own experience with PCOS.
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“I was a registered dietitian when I was diagnosed with PCOS, and despite doing everything I was taught about nutrition, nothing worked,” she said. “It wasn’t until I discovered the connection between insulin and PCOS that everything changed. Lilli was built from that experience, from the research that followed, and from the thousands of women who have shared the same frustration.”
Chappell added that most other apps focus on calorie counting, general wellness or fertility tracking, such as MyFitnessPal, Flo, Clue, Ovia and Noom.
“None of these apps track PCOS-specific symptoms, offer insulin testing or lab interpretation, or provide meal plans and recipes specifically designed to keep insulin levels low. That’s where Lilli is different,” she declared. “We’re the first and only app built specifically for reversing insulin resistance in PCOS.”
Ultimately, the company aims to “change the way PCOS is diagnosed and treated,” Chappell stated. Lilli Health is also pursuing FDA clearance for the Lilli App as software as a medical device.
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