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Pharma

Targacept confident in ADHD compound, plans new trials by 2012

AstraZeneca‘s (NYSE:AZN) decision earlier this year to not license Targacept‘s (NASDAQ:TRGT) compound for attention-deficit/hyperactivity disorder was seen by some as a no confidence vote in the molecule. But Don deBethizy, CEO of Winston-Salem, North Carolina-based Targacept, is making a case for TC-5619, which showed positive results for schizophrenia but failed in a separate ADHD study […]

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Targacept’s $75M stock offering targets cognitive disorders R&D

Now that AstraZeneca (NYSE:AZN) has determined it won’t license Targacept‘s compound for schizophrenia, the drug development company is preparing to raise up to $75 million to develop the drug candidate on its own. Winston-Salem,  North Carolina-based Targacept (NASDAQ:TRGT) set the dollar target in a preliminary prospectus filed Tuesday with the U.S. Securities and Exchange Commission. […]

Pharma

AstraZeneca declines option to license Targacept schizophrenia compound

If the compound Targacept is developing for patients with schizophrenia has a future as a commercialized drug, it will get there without drug partner AstraZeneca. AstraZeneca (NYSE:AZN) is passing up its option to license the drug compound from Winston-Salem, North Carolina drug development company Targacept (NASDAQ:TRGT). The compound, called TC-5619, showed promising results in phase […]

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AstraZeneca, Pozen file patent suit to protect arthritis drug Vimovo

North Carolina pharmaceutical company Pozen (NASDAQ:POZN) and drug partner AstraZeneca (NYSE:AZN) are taking legal action to block a generic competitor to osteoarthritis drug Vimovo. The companies have filed a patent infringement lawsuit in U.S. District Court for the District of New Jersey against India-based generics company Dr. Reddy’s Laboratories (NYSE:RDY). Dr. Reddy’s notified both companies […]

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Targacept ADHD drug fails in study; still shows promise for schizophrenia

An experimental attention deficit-hyperactivity disorder (ADHD) drug being developed by Targacept in partnership with AstraZeneca (NYSE:AZN) has failed to hit targets set for a mid-stage clinical trial. Winston-Salem, North Carolina-based Targacept, (NASDAQ:TRGT) said results from a phase 2 proof-of-concept trial for the TC-5619 showed  that although patients experienced no adverse effects from the compound, the […]

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$200M AstraZeneca payment lifts Targacept earnings

Targacept's collaboration and licensing agreement with AstraZeneca is starting to show on its financial results as the Winston-Salem, North Carolina drug company started to receive some of the $200 million payment from the 2009 agreement. The compound that AstraZeneca has licensed will be advancing into late-stage clinical trials later this year.