Massachusetts immuno-oncology startup Advantagene just raised $5 million of a proposed $35 million round, according to a regulatory filing.
The company is developing a prostate cancer vaccine called ProstAtak that’s in Phase 3 development – though its gene-mediate cytotoxic approach could be applied to several other solid tumor cancers, the company says.
ProstAtak, much like Advantagene’s other cancer immunotherapy approaches, melds radiation with its biologic to create cancer cell death. It’s also testing the drug in adult and pediatric brain cancer, pancreatic cancer, malignant pleural effusion and mesothelioma.
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The Phase 3 study started in 2011 and is expected to wrap up next year; it’s testing the vaccine in 711 patients.