Daily

GSK gene therapy close to EU submission, CRISPR closes new cash, Takeda settles Actos (Morning Read)

Takeda has reached a settle over the cancer lawsuits connected to Actos diabetes treatment. Three big players came in on CRISPR Therapeutics’ round. And it looks like GlaxoSmithKline will be the first big pharma company to file for marketing approval for a gene therapy in to combat adenosine deaminase severe combined immune deficiency in Europe.

TOP STORIES

Takeda has agreed to pay $2.4 billion to settle the Actos cancer lawsuits.

NEA, Celgene and SROne have lead a $60 million+ round for CRISPR Therapeutics.

It looks like GlaxoSmithKline will be the first big pharma company to file for marketing approval for a gene therapy to combat adenosine deaminase severe combined immune deficiency when it submits its drug for ADA-SCID in Europe, according to a Fox News report referencing people familiar with the situation. The condition, which leaves patients extremely vulnerable to infection, affects about 350 people worldwide.

LIFE SCIENCE

AstraZeneca’s heart drug Brilinta will get fast-tracked by the FDA.

Here’s a wrap up of earnings results from Merck, Pfizer and Bristol-Myers Squibb.

presented by

Drug testing company Cordant Health Solutions has raised $12.8 million as the combination of 5 formerly independent laboratories seeks to combine forces in the fragmented industry.

Sanofi’s diabetes treatment Toujeo gets approved in the EU.

Boston Scientific agrees to a $119 million settlement of product liability lawsuits brought over its pelvic mesh offerings.

Cardinal Health confirmed a report by Columbus Business Journal that it acquired Nashville based specialty pharmaceutical distributor Metro Medical Supply.

PAYERS-PROVIDERS

Assurant Health is looking for a buyer for its money-hemmorhaging health insurance business.

It’s official: avian flu is back this fall.

Health in the city of Baltimore.

The American Heart Association announced the cancellation of a medical conference in Baltimore due to the unrest in the city. QCOR 2015, the Quality of Care and Outcomes Research Scientific Sessions, would have been held at the Hilton Baltimore from Wednesday to Friday this week.

The aftermath of the Nepal earthquake brings a risk of disease outbreaks, including measles and diarrheal diseases.

A comparison of three treatments for narcotic painkiller addiction found that patients given the medication buprenorphine actually in the emergency department have more success than those given only referrals.

TECH

Google’s biotech Calico has found a new spot inside the Buck Institute for Research on Aging in Novato, Calif.

For South San Francisco-based Calico, the deal gives the biotech a chance to fund new work on projects “ranging from basic biology to potential therapies for age-related diseases,” which is Calico’s area of expertise. Calico in turn will get an exclusive option on the rights to any discoveries made in the collaboration, with the biotech establishing its own operations at the Buck.

Members of Dallas-based Health Wildcatters‘s second class raised a total of $4.5 million.

Doctor referral coordinator startup Fibroblast added Illinois’ largest Catholic hospital as a customer.

POLITICS

Signs there could be a $1 billion increase in NIH funding – maybe.

Can’t agree on Medicaid expansion? Just take your ball and go home early.

Conservative members of Congress are putting the final touches on a new Obamacare replacement plan. They reportedly plan to release the plan right before the Supreme Court ruling on the ACA.

The U.S. Food and Drug Administration approved the first generic versions of Abilify (aripiprazole), an atypical antipsychotic drug approved to treat schizophrenia and bipolar disorder.

A LITTLE EXTRA

Is the universe actually two-dimensional, but we perceive it as three-dimensional, much like a hologram?

This amazing idea is known as the ‘holographic principle’ and arises from string theory. String theory says that the gravity in the universe is made up of thin, vibrating strings called gravitons. These strings make up the holograms of events that happen in 3D space within a flat cosmos. They contain the information that a 3D object would have, for example its volume. So if you want to know what’s happening inside a ball, you can find out everything you need to know just by looking at the surface.

The Morning Read provides a 24-hour wrap up of everything else healthcare’s innovators need to know about the business of medicine (and beyond). The author of The Read published it but all full-time MedCity News journalists contribute to its content.

Topics