Devices & Diagnostics, Startups

Just like kidney stone therapy: Shockwave Medical gets $40M for tech that breaks up calcium plaques in advanced vascular disease

Shockwave Medical just got $40M for its technology that breaks up plaques in vascular disease – much like the lithotripsy used to treat kidney stones.

Bay Area device startup Shockwave Medical just raised $40 million to build out its balloon catheters to be used in peripheral, coronary and aortic valve surgeries. It uses the same basic technology used to break up kidney stones – but applies it to the calcium plaques built up in patients with advanced vascular disease.

The round was led by Sofinnova Partners and new investor Venrock, with other investors including RA Capital, Deerfield, Sectoral Asset Management, Ally Bridge Group and two undisclosed, large-cap strategics.

The line of catheters, called Lithoplasty, are particularly geared toward the atherosclerosis typical of advanced vascular disease, where blood flow is limited.

“These deposits are difficult to treat because they limit the effectiveness of current endovascular devices, making today’s interventions challenging and prone to both procedural and longterm failure,” Shockwave says.

This balloon-based technology uses the same kinds of pulsations used in kidney stone lithotripsy – disrupting the superficial and deep calcium buildup and normalizes vessels before low-pressure balloon dilation. It’s designed to be gentle inside these soft tissues, but is “hard on calcium.”

The company has a CE mark for use in Europe, but isn’t yet available in the U.S.

Here’s a video of how it works:

[vimeo 110833330 w=500 h=281]

Shockwave Lithoplasty(tm) from Shockwave on Vimeo.