MedCitizens

StartUPDATES: New developments from healthcare startups

This week, read new developments at Carrum Health, Seven Bridges, CARISMA Therapeutics, and more.

Vector illustration - Startup

Seven Bridges recently announced the formation of its strategic advisory board tasked with advising Seven Bridges leadership team in its mission to accelerate scientific discovery and speed the path from raw experimental data to new treatments and diagnostics. The appointment of three leaders with significant experience in healthcare and artificial intelligence will aid the company exploring new health-focused opportunities and bolster the company’s work with biopharmaceutical and academic researchers to significantly decrease the time, cost, and risk in the discovery-through-commercialization cycle for novel precision medicines and therapies.

“Our strategic advisory board will contribute to our business strategy and technology roadmap, helping us better understand the links between genomic data and health outcomes,” said Bill Moss, chief executive officer of Seven Bridges. “We look forward to expanding the breadth of expertise represented and building the board’s capabilities over the coming years.”

Joining the Strategic Advisory Board are:

David Ledbetter, Ph.D., chief clinical officer at Dascena, brings Seven Bridges tremendous experience with human genetics. He was previously executive vice president and chief scientific officer at Geisinger Health System, a professor of human genetics at Emory University School of Medicine, University of Chicago Medicine, and Baylor College of Medicine, as well as branch chief in the diagnostic development branch at the National Human Genome Research Institute. Click here to learn more.


In a first-of-its-kind study of bundled payments for commercially insured populations, RAND Corporation highlights the significant financial savings that can be achieved through Carrum Health‘s digital Centers of Excellence (COE) platform. The study, published in Health Affairs, the leading peer-reviewed journal of health policy thought and research, highlighted a more than 45% per procedure savings when procedures were performed through Carrum Health.

Overall, employers achieved an 11% medical cost reduction after implementing Carrum Health across all covered procedures, including those not performed through the Carrum Health benefit. Patients also saved money as cost-sharing payments were waived for the 21% of patients who went through the program.

“Our analysis of Carrum Health’s market-leading COE platform shows that both employers and patients can see immediate and significant savings on completed surgeries, while getting high-quality care from the top hospitals around the country,” said Christopher M. Whaley, Ph.D., healthcare policy researcher for RAND Corporation and author of the study.

“We launched Carrum Health to catalyze the transition of the healthcare payment model from the inefficient fee-for-service system to value-based care, leveraging bundled payments. Bundled payments are a powerful vehicle that align incentives across purchasers, members and providers, reduce costs and improve health outcomes,” said Sach Jain, CEO and founder of Carrum Health. “RAND’s analysis of bundled payments using Carrum Health’s data validates that, when done right, bundled offerings definitively reduce medical spending while still delivering excellent outcomes.”


CARISMA Therapeutics Inc., a biopharmaceutical business that discovers and develops innovative immunotherapies, has had a second closing of its Series B equity financing, bringing the total amount raised in this round to $59 million. The additional funding came from new investor 4BIO Capital and founding investors, IP Group and Penn Medicine. They join the initial Series B investor syndicate of SymBiosis II, Solasta Ventures, Livzon Pharmaceuticals Group, AbbVie Ventures, HealthCap, Wellington Partners, TPG Biotech, Agent Capital and MRL Ventures Fund. To learn more, click here.


A former health system CEO, health insurance executive, and population health professional have joined forces to launch ZealCare. The North Carolina startup seeks to help people with complex chronic conditions through a combination o virtual care and services validated by Duke University Center for Personalized Health Care. To learn more, click here.

Picture: akindo, Getty Images